Non-coding RNA genes have been recently used as biomarkers and therapeutic targets in cancer. Using an integrative genomic data analysis pipeline, this project provided a comprehensive resource of cancer-specific non-coding RNA genes in six cancers including breast, skin, blood, liver, bone, and lung cancers. This extensive resource can be used in the future to better understand the underlying genetic risk factors that contribute to cancer.
Resource available: http://ncrna.ictic.sharif.edu/
Research paper: Somatic point mutations are enriched in long non-coding RNAs with possible regulatory function in breast cancer | bioRxiv
Project lead: Dr Hamid Alinejad-Rokny